Irritable Bowel Syndrome (IBS) Clinical Trials at Riverside Clinical Research

What Irritable Bowel Syndrome Is…

From time to time, do you experience belly discomfort or have pain or trouble with bowel habits? Maybe you “go” a little more often than you should or not as often as you should? Have you been noticing that your stool is not quite as it should be – whether that is too thin, too hard or soft and liquidy? If so, you may have Irritable Bowel Syndrome (IBS).

Irritable Bowel Syndrome, a chronic gastrointestinal disorder that affects the large intestine, is very common. It’s not life threatening, nor does it lead to more severe conditions, such as ulcerative colitis, Crohn’s disease or even colon cancer; but it can certainly negatively affect your work habits and other activities of daily living.

Who Irritable Bowel Syndrome Affects…

There are more than 3 million cases of Irritable Bowel Syndrome reported per year in the United States alone and 25 million to 45 million people in the United States suffer from IBS. Those cases, however, are not typically severe. More severe cases are much less common. 

This intestinal disorder is most likely to first appear in younger people – mostly teens to those in their early forties – and can last from several years to an entire lifetime. Irritable Bowel Syndrome is found more often in females, most experiencing worsening symptoms during menstrual periods. This leads researchers to believe that hormonal changes may be a factor in Irritable Bowel Syndrome. Family history can also increase the likelihood of IBS.

Symptoms Irritable Bowel Syndrome Can Cause…

Irritable Bowel Syndrome symptoms can include gas, bloating, abdominal pain, indigestion, changes in patterns of bowel movements, mucus in the stool, diarrhea on its own or diarrhea alternating with constipation. If symptoms are severe, they can even lead to mood disorders and a compromised quality of life.

Other related symptoms, including rectal bleeding, anemia, weight loss, diarrhea at night or persistent pain that is not remedied by releasing gas or emptying bowels, could indicate a more serious problem, such as colon cancer. Anyone experiencing any of these symptoms should immediately consult a physician.

Treatment for Irritable Bowel Syndrome…

Current treatment options can help manage the symptoms of Irritable Bowel Syndrome, but there is no known cure. 

Nutrition is an important part of Irritable Bowel Syndrome symptom management. Those with IBS should obviously avoid foods that trigger episodes, as well as carbonated beverages and alcohol. Also avoid gluten, fructose and lactose. Foods that should be heartily consumed are those rich in fiber, including broccoli, lentils and beans.

Self-care, including stress management, regular exercise and adequate sleep, is recommended. Counseling may also help to deal with stress in an effort to prevent or ease Irritable Bowel Syndrome symptoms.

Medication that is currently used to treat the symptoms of Irritable Bowel Syndrome includes anti-diarrheal drugs for diarrhea; anticholinergics for the relief of intestinal spasms; anticonvulsants for pain and bloating; tricyclic antidepressants for depression and severe pain; and selective serotonin reuptake inhibitors (SSRIs) to relieve depression and pain, as well as constipation.

What Causes Irritable Bowel Syndrome…

The causes of Irritable Bowel Syndrome are unknown, but factors found likely to contribute to IBS include intestinal inflammation, strong intestinal muscle contractions and cramping, abnormalities within the intestinal nervous system, severe infections such as gastroenteritis or any changes to gut microflora, which are microorganisms that occur naturally within the digestive tract. Microflora abnormalities and bacteria can produce toxic by-products which can create very serious issues such as long-term illness and chronic degeneration.

Prevention of Irritable Bowel Syndrome…

There is no proven prevention of Irritable Bowel Syndrome, but avoiding stress when there is a family history of IBS and consuming adequate portions of daily fiber seem to help. 

Common Tests and Procedures for Irritable Bowel Syndrome…

X-rays and CT scans of the abdomen are typically performed to rule out any other possible causes of abdominal pain. Stool tests are for bacteria and parasite discovery. Breath tests are conducted to check for bacterial growth within the small intestine. An endoscopic procedure is conducted to determine if there are any intestinal blockages. Tests for lactose intolerance and gluten allergies are also typically performed.

Riverside Clinical Research and You…

Clinical research is vital to the evolving and progressive science of healthcare. By conducting Phase I, II, III and IV studies to support requirements leading to new drug applications, Riverside Clinical Research continually determines the safety and effectiveness of medications. Through Riverside Clinical Research studies, we make it our mission to discover innovative methods of the prevention, detection, diagnosis, control and treatment of illnesses – like Irritable Bowel Syndrome.

Our goal, at Riverside Clinical Research, is to make the world a better place through clinical research that breaks new ground and leads the way to better care. Today, there is no more necessary and noble undertaking. Our future depends on it. 

Have you been diagnosed with Irritable Bowel Syndrome or suffer from what you think may be symptoms of Irritable Bowel Syndrome? Would you like to join Riverside Clinical Research in our quest to improve lives through medical advances? 

Riverside Clinical Research volunteers not only markedly contribute to significant breakthroughs in medicine; they are often able to benefit from innovative medical treatments before they are made available to the general public. In addition, Riverside Clinical Research volunteers are paid for their time, there are no costs for the medical procedures or treatments provided and there is no insurance necessary to participate.

You can reach Riverside Clinical Research by calling 386-428-7730 Monday through Thursday from 7 a.m. to 5 p.m. or Friday from 7 a.m. to 12 p.m.; or email your questions to You can also learn more about the clinical research trials at Riverside Clinical Research by accessing our patient portal which can be found on our website. Riverside Clinical Research is conveniently located at 1410 S. Ridgewood Avenue in Edgewater.