Liver Impairment

Velocity Clinical Research Liver Impairment Studies

In times like these, people are choosing less and less to make those recommended visits to the doctor. Our current conditions may have added stress to our lives as well as our bank accounts; but there are some doctor visits that are simply imperative to make. One is if you are suffering from liver impairment.

Whether you have been stressing about seeing the doctor for liver impairment because you have no insurance, you could use some extra cash or you simply want to be part of the advancement of medicine and betterment of lives; volunteering for a Velocity Clinical Research study may be the solution for which you are searching.

Velocity Clinical Research is currently conducting clinical trials for liver impairment and seeking men and women participants between the ages of 18 and 25 with hepatic impairment. Study related medical care, medical exams and physician supervision will be provided at no cost and there is absolutely no insurance needed. Velocity Clinical Research liver impairment study participants are also entitled to payment for time and travel, with reimbursements up to $2,150 for 11 visits. 

You can call Velocity Clinical Research at 386-428-7730 Monday through Thursday from 7 a.m. to 5 p.m. or Friday from 7 a.m. to 12 p.m. for more information or to see if you qualify. Velocity Clinical Research, conveniently located at 1410 S. Ridgewood Avenue in Edgewater, is a well-respected research facility with doctors and research professionals that have over 50 years of combined clinical trial experience and work closely with clinical trial volunteers to monitor and assess the benefits and effectiveness of medication. 

Liver Functions

The liver, one of the body’s most important organs, performs vital functions including building the immunity necessary to fight infection and producing bile which breaks down food to aid in digestion. The liver also metabolizes certain drugs, removes toxins and produces proteins, many of which are responsible for blood clotting. Additionally, the liver is responsible for converting nutrients into substances our body can use, storing those substances and then supplying them to our cells whenever they are required. Subsequently, proper liver function is essential to quality of life and liver impairment can be both dangerous and debilitating.

Hepatic Impairment

Complications associated with hepatic impairment can include fluid build-up, a decrease in necessary blood clotting, infections such as pneumonia, kidney failure and severe liver impairment can even lead to death. 

There are four stages of hepatic impairment progression. In the first stage, the liver may be tender and/or inflamed. If the inflammation remains untreated, that brings us to stage two. Stage two hepatic impairment is the point at which scarring results. As scar tissue builds up, it will impede blood flow. Cirrhosis of the liver is considered stage three of hepatic impairment. This is the stage where the amount of scar tissue exceeds that of healthy tissue, causing the liver to function even more poorly. Stage four is liver failure which, without a liver transplant, can result in death.

Common Causes of Hepatic Impairment

Typically, liver impairment will occur gradually over time, developing over a period of many years. Chronic liver impairment is often the result of cirrhosis caused by long-term alcohol abuse. Cirrhosis of the liver can be characterized by fluid imbalances presenting as abdominal swelling and/or swollen ankles combined with skinny arms and legs. Other symptoms of chronic liver impairment may include jaundice, skin spots, diminishing appetite, nausea, diarrhea, fatigue and hepatic encephalopathy.

Acute liver failure differs in that it is a condition which can occur very quickly. In fact, with acute liver failure, the liver can stop properly functioning within a matter of days or weeks. Acute liver failure can be attributed to acetaminophen overdose, viruses including hepatitis, negative reactions to prescriptions, septic shock and industrial toxins.

Prevention and Treatment of Hepatic Impairment

There are a variety of measures recommended to prevent liver impairment, such as maintaining a proper diet and a healthy weight, limiting alcohol consumption, practicing good hygiene; using condoms during intercourse and getting vaccinated for hepatitis. Other steps that should be taken to help prevent hepatic impairment are to use a reputable and sanitary vendor if getting a tattoo or body piercing, and never sharing needles or even toiletry items. 

There are a variety of ways to treat liver impairment. Medications, including acetylcysteine which can reverse acute liver damage, are one way to treat liver impairment. Also, the supportive care provided by hospitals can sometimes help a liver recover on its own; and, in the most severe cases of hepatic impairment, a liver transplant may be recommended.

Diagnosing Hepatic Impairment

Since the liver is responsible for blood clotting, blood tests are conducted. Imaging tests including ultrasounds, CTs and MRIs are also used to obtain optimal views of the liver. Biopsies are taken to study liver tissue.

Common Types of Hepatic Impairment

Common conditions that impair liver function include a fatty liver, which can lead to liver cancer and cirrhosis of the liver; non-alcoholic fatty liver disease, with symptoms including fatigue and/or abdominal pain; amyloidosis, which is a protein build-up in the liver tissue, possibly causing fatigue, diarrhea, weight loss, bleeding, numbness, dizziness and swelling of the legs, tongue or spleen; and cirrhosis of the liver, which can cause fatigue, weakness and lower leg swelling. More serious complications associated with cirrhosis can include infections, bleeding from dilated veins in the stomach and esophagus and a greater chance of liver cancer.